Experimental protocol diagram 3. Forty-eight male SD rats were randomly divided into 6 groups(n = 8 each): Sham, CON, EA, MW167, EA + MW167 and EA + DMSO group. At 30 min before MCAO(yellow arrow), intraventricular injections were performed. MW167 and DMSO were given respectively. At 24 h, 48 h and 72 h after ischemia/reperfusion (red arrow), neurological function scores were assessed in the 6 groups respectively. At 72 h after ischemia/reperfusion, all rats were anesthetized and killed, the infarct volumes were measured.