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Figure 2 | BMC Neuroscience

Figure 2

From: Failure of delayed nonsynaptic neuronal plasticity underlies age-associated long-term associative memory impairment

Figure 2

Electrophysiological assessment of CGCs in Junior and Senior animals. A. Examples of intracellular recording of spontaneous electrical activity in CGCs of junior and senior conditioned (CS-UCS) and unconditioned control (CS-DS) animals. B. Average number of spontaneous action potentials of CGCs in both junior and senior conditioned and control animals. Aged CGCs showed a significantly lower spontaneous action potential firing rate than junior CGCs No significant difference was observed between the control and conditioned groups within each age category. C. Resting membrane potential of junior CGCs was more depolarized compared with senior CGCs. Behavioural conditioning further depolarized resting membrane potential in junior but not in senior animals. * = p < 0.05, *** = p < 0.001, ns = non-significant.

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BMC Neuroscience

ISSN: 1471-2202

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