Figure 1
Sleep-wake activity with and without shift work. Permanent shifts are introduced on the 3rd day of the simulation between 22.00 and 06.00. Variables shown on the plot are: mean firing rate across the neurons in (A) monoaminergic and (B) ventrolateral preoptic nuclei, (C) homeostatic sleep drive, (D) circadian process, (E) total sleep drive, and (F) intensity of light to which the worker is exposed.