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Table 2 Genetic interaction with Dys and Dg in photoreceptor axon path finding

From: New Dystrophin/Dystroglycan interactors control neuron behavior in Drosophila eye

Gene name

Defective lamina plexuses (%)

n, analyzed optic lobes

χ2-value

Defective lamina plexuses (%)

n, analyzed optic lobes

χ2-value

Defective lamina plexuses (%)

n, analyzed optic lobes

χ2-value

 

DysDf x

DysDf x

DysDf x

DgO86x

DgO86x

DgO86x

OregonR x

OregonR x

OregonR x

OregonR

9.8

61

1.1°

17.5

40

6.0° *

4.9

41

-

DysDf

42.9

49

28.8 ° ***

36.4

55

22.5 ° ***

9.8

61

1.1°

Dg[O86]

36.4

55

22.5 ° ***

57.5

40

42.7 ° ***

17.5

40

6.0° *

Dg[O55]

-

-

-

42.1

19

27.9 ° ***

-

-

-

Cam[n339]

37.5

48

15.0 ***

33.3

39

4.3 *

0.0

9

3.0

Capt[E636]

26.7

45

6.9 **

29.8

47

2.7

2.9

35

0.1

CG34400[c05107]

30.9

42

9.9 **

35.5

31

5.4 *

14.3

35

3.7

CG7845[EMS-Mod4] 1

11.1

9

4.0 × 10-3

5.6

18

5.2 *

-

-

-

chif[BG02820]

14.3

14

0.5

6.3

16

4.4 *

-

-

-

Fhos[A055]

19.0

21

2.3

8.3

12

2.6

-

-

-

Fkbp13[P962]

21.4

14

3.6

11.1

9

1.0

-

-

-

Grh[IM]

25.0

24

5.8 *

13.0

23

0.4

10.0

20

1.2

Lis1[k11702]

17.8

28

1.8

31.2

16

3.3

7.7

13

0.3

Lis1[k13209] 2

30.3

33

9.5**

33.3

12

4.3*

37.5

16

23.7***

Lis1[k13209]

33.3

12

11.8***

11.1

9

1.0

28.6

14

15.5***

mbl[E27]

34.3

35

12.5 ***

21.0

38

0.2

0.0

7

3.0

nAcRα-30D[EY13897]

0.0

9

7.9 *

12.5

8

0.5

-

-

-

Nrk[k14301] 2

23.7

38

4.9 *

13.3

15

0.3

0.0

7

3.0

POSH[k15815] 2

9.1

22

5.0 × 10-3

21.7

23

0.3

-

-

-

Rack1[EY00128] 2

0.0

13

7.9 *

21.7

23

0.3

-

-

-

robo[2]

9.1

11

4.0 × 10-3

26.1

23

1.3

-

-

-

SP2353[MB00605]

5.0

20

1.0

22.2

18

0.3

-

-

-

vimar[EY09646]

21.4

42

3.6

27.3

22

1.7

-

-

-

  1. all mutant alleles were obtained from BDSC, all RNAi mutants - from VDRC, 1 - described previously [70], 2 - from DGRC
  2. ° - compares to Oregon R