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Figure 7 | BMC Neuroscience

Figure 7

From: In Vitro Assessment of Tobacco Smoke Toxicity at the BBB: Do Antioxidant Supplements Have a Protective Role?

Figure 7

BBB glucose metabolism is affected by TS exposure. The ratio between glucose consumption and lactate production is not affected by vitamins supplementation (C+E) (Panel A). Note that a glucose consumption/lactate production ratio ≈ 1 indicates that at list 50% of glucose undergoes oxidative metabolism (Krebs cycle). TS caused a decrease in glucose consumption paralleled by an in lactate production (Panel B) suggesting that a shift toward a non-oxidative glucose metabolism occurred. This metabolic shift was gradually reversed by antioxidant vitamins supplementation (C+E). The asterisk "*" indicates a statistically significant difference (p < 0.05) versus control. The described experiments were performed in quadruplicates (n = 4).

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