Figure 6

Amperometric determination of NO during and after TS exposure. (Panel A) Note the transient surge in the medium levels of NO immediately after TS exposure followed by a steady decline that brought the NO to below baseline levels during the recovery time. (Panel B) Pre-treatment with vitamins C and E did not prevent the reduction of NO bioavailability nor accelerated the return to a baseline level but reduced the NO decline during the initial phase of TS exposure (Panel A -right). Please note that reading conversion of the NO sensors was ≅ 1.5pA/nM ± 3%. The described experiments were performed in quadruplicates (n = 4).