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Figure 9 | BMC Neuroscience

Figure 9

From: Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons

Figure 9

Effect of GSPE on 0.1 mM [Mg2+] o and oxygen glucose deprivation-induced neurotoxicity. A: Hippocampal neurons were exposed to normal medium or 0.1 mM [Mg2+]o-containing medium with or without GSPE (6 μg/ml, n = 8) for 20-24 h. B: Hippocampal neurons were exposed to normal or oxygen glucose deprived conditions without GSPE (OGD, n = 8) or with GSPE (6 μg/ml, n = 8) for 90 min. After 20-24 h, the same fields of cells were recounted. Data are expressed as the mean ± SEM. *P < 0.001 relative to the control, # P < 0.05 relative to 0.1 mM [Mg2+]o or OGD (ANOVA with Bonferroni's test).

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