Figure 3
Effect of GSPE on NMDA-induced [Ca2+] i response. Reproducible [Ca2+]i increase was induced by treatment for 1 min with 100 μM NMDA at 20-min intervals (control, n = 11). Pretreatment with GSPE (6 μg/ml) for 5 min decreased the NMDA-induced response (GSPE, n = 15). Data are expressed as the mean ± SEM. *P < 0.05 relative to NMDA (unpaired Student's t-test).