Blunting type 1 insulin-like growth factor receptor expression exacerbates neuronal apoptosis following hypoxic/ischemic injury

Table 1 The number of mice that die during hypoxia/ischemia (H/I) and within 48 hr following H/I insult.

Control mice (n = 83) and nes-igf1r^-/Wtmice (n = 45) were subjected to H/I insult, as described in the Methods section. The percentage of mice dying during common carotid artery ligation surgery, hypoxia treatment, or 48 hours after H/I insult in each group is reported in the parentheses. Statistical analysis was done using X², assisted with the software SigmaStat for Windows (SPSS, Inc., Chicago, IL). No significance was observed.