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Table 2 Effect of EGCG treatment on the number of surviving motoneurons and percentage of cell loss in the lesioned side of DMN and HN at 3, 7, 14 and 28 days following PNCI

From: (-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury

Days postoperative

Hypoglossal nucleus

 

Sham

Saline

EGCG

(10 mg/kg)

EGCG

(25 mg/kg)

EGCG

(50 mg/kg)

3

1416 ± 11

1405 ± 8

1408 ± 9

1398 ± 8

1399 ± 9

 

-

1 ± 0.6%

1 ± 0.6%

1 ± 0.8%

1 ± 0.9%

7

1408 ± 10

1294 ± 18

1304 ± 17

1360 ± 11*

1365 ± 7*

 

-

9 ± 1.7%

8 ± 1.9%

4 ± 1.2%*

4 ± 1.0%*

14

1411 ± 11

1212 ± 31

1238 ± 20

1318 ± 10*

1331 ± 7*

 

-

14 ± 2.0%

12 ± 2.0%

7 ± 1.0%*

6 ± 1.0%*

28

1397 ± 8

1165 ± 20

1175 ± 30

1291 ± 5*

1301 ± 5*

 

-

18 ± 2.0%

17 ± 2.0%

9 ± 1.0%*

8 ± 1.0%*

Days postoperative

Dorsal motor nucleus of vagus nerve

 

Sham

Saline

EGCG

(10 mg/kg)

EGCG

(25 mg/kg)

EGCG

(50 mg/kg)

3

1284 ± 10

1277 ± 13

1286 ± 8

1293 ± 8

1289 ± 7

 

-

1 ± 0.5%

0 ± 0.7%

0 ± 0.6%

0 ± 0.7%

7

1292 ± 8

1182 ± 19

1185 ± 16

1227 ± 11*

1235 ± 8*

 

-

8 ± 1.5%

8 ± 1.6%

4 ± 0.7%*

4 ± 0.7%*

14

1289 ± 11

1055 ± 20

1079 ± 14

1182 ± 13*

1192 ± 7*

 

-

18 ± 1.3%

16 ± 1.4%

8 ± 0.7%*

7 ± 1.0%*

28

1283 ± 8

952 ± 21

983 ± 17

1021 ± 15*

1091 ± 27*

 

-

26 ± 1.2%

23 ± 1.4%

20 ± 1.3%*

15 ± 2.3%*

  1. *, p < 0.05 when compared with the saline-treated group