Figure 4From: Human cerebrovascular contractile receptors are upregulated via a B-Raf/MEK/ERK-sensitive signaling pathwayPhosphorylated B-Raf (p-B-Raf) expression in human cerebral vessels. Cultured vessel with vehicle only shows increased immunoreactivity compared with fresh, non-cultured vessel. This effect was markedly reduced after treatment with SB-590885 and SB-386023. Data were obtained with epifluorescence microscopy. Insert: higher magnification, scale bar 50 μm.Back to article page