Analysis of epileptic EEG signal bursts. (A) Comparison of the average number of threshold-exceeding raw EEG peaks (greater than 4.75 standard deviations from the individual baseline activity of the raw EEG data) between the FUS-treated and untreated groups. (B) Comparison of the average number of EEG theta peaks exceeding the absolute magnitude above the threshold (4.75 standard deviations from the individual baseline theta activity) between the same two groups. Red bars indicate Group 1 (the FUS-treated PTZ group: PTZ(+)/FUS(+)), and blue bars indicate Group 2 (the untreated epileptic group: PTZ(+)/FUS(-)). As shown in both graphs, there were no significant differences between the two groups before the sonication. Red brackets indicate statistically significant differences (p < 0.05) within the FUS-treated group, and green brackets indicate statistically significant differences between the two groups. Error bars indicate standard errors of the mean.