Table 2 [3H]-paroxetine binding parameters(a) in mouse membranes.
From: Serotonin transporter (SERT) and translocator protein (TSPO) expression in the obese ob/ob mouse
Brain: | Kd (nM) | Bmax(fmol/mg protein) |
|---|---|---|
ob/ob Mutant | 0.1 ± 0.01 | 368 ± 17.5 |
Wild Type | 0.09 ± 0.01 | 341 ± 18.0 |
Platelets: | Kd (nM) | B max (fmol/mg protein) |
ob/ob Mutant | 0.09 ± 0.008 | 18680 ± 2278 |
Wild Type | 0.08 ± 0.01 | 14830 ± 1722 |