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Table 2 Cyto-chemokine production at baseline and after 1 month of therapy in SC patients

From: Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls

Variable Pre treatment Post treatment Wilcoxon U test p-value
MCP-1    
   Basal 11360.9 ± 759.2 10840.5 ± 661.5 0.012
   LPS 19579.6 ± 803.9 19321.5 ± 1373.5 0.005
RANTES    
   Basal 1071.5 ± 174.9 1161.2 ± 134.4 0.005
   LPS 11755.4 ± 451.3 12125.0 ± 502.8 0.005
IL-18    
   Basal 62.9 ± 4.9 68.3 ± 5.7 0.005
   LPS 298.0 ± 15.1 317.7 ± 14.2 0.005
  1. Mean ± standard deviation of RANTES, MCP-1 and IL-18 levels (pg/ml) released by non-stimulated and LPS-stimulated PBMC from 10 SC patients at time of enrolment and after 1 months of treatment with atypical antipsychotic drugs.