Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls

BMC Neuroscience

Table 2 Cyto-chemokine production at baseline and after 1 month of therapy in SC patients

Variable	Pre treatment	Post treatment	Wilcoxon U test p-value
MCP-1
Basal	11360.9 ± 759.2	10840.5 ± 661.5	0.012
LPS	19579.6 ± 803.9	19321.5 ± 1373.5	0.005
RANTES
Basal	1071.5 ± 174.9	1161.2 ± 134.4	0.005
LPS	11755.4 ± 451.3	12125.0 ± 502.8	0.005
IL-18
Basal	62.9 ± 4.9	68.3 ± 5.7	0.005
LPS	298.0 ± 15.1	317.7 ± 14.2	0.005

Mean ± standard deviation of RANTES, MCP-1 and IL-18 levels (pg/ml) released by non-stimulated and LPS-stimulated PBMC from 10 SC patients at time of enrolment and after 1 months of treatment with atypical antipsychotic drugs.

ISSN: 1471-2202