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Table 2 Correlation data for candidate genes.

From: Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway

Column1 Gene Slope 95% Confidence Intervals Goodness of Fit, R square P value n
Ad libitum Pfn2 0.57 -0.1531 to 1.286 0.29 0.107 10
Chow fed Ntrk2 0.55 0.1165 to 0.9898 0.52 0.019 10
Mice Bdnf -0.47 -0.7881 to -0.1488 0.63 0.011 10
  Prkacb -0.06 -0.3902 to 0.2681 0.02 0.680 10
  Vamp2 0.29 -2.319 to 2.905 0.01 0.793 8
  Stat3 0.50 -1.635 to 2.626 0.05 0.590 8
  Nln 0.63 -1.469 to 2.737 0.08 0.489 8
  Btbd12 2.38 -3.681 to 8.433 0.13 0.374 8
  Zbtb20 2.29 -1.129 to 5.710 0.31 0.152 8
  Atf7ip - - - - -
Food deprived pfn2 1.19 0.2082 to 2.171 0.66 0.026 8
mice Ntrk2 0.09 -0.54 to 0.73 0.03 0.724 8
  Bdnf 0.06 -52 to 0.64 0.02 0.792 8
  Prkacb -0.04 -1.198 to 1.113 0.00 0.932 8
  Vamp2 0.71 -0.5620 to 1.983 0.24 0.221 8
  Stat3 0.54 0.01046 to 1.078 0.51 0.047 8
  Nln 0.71 -0.4190 to 1.832 0.28 0.175 8
  Btbd12 1.69 0.1775 to 3.198 0.55 0.034 8
  Zbtb20 0.65 -0.3582 to 1.664 0.29 0.165 8
  Atf7ip - - - - -
  1. The expression of genes in bold text are significantly correlated to expression of Fto (p < 0.05). Genes in cursive text were run on chow fed mice in the 16 hour food restriction paradigm. Hypothalamic expression of Ntrk2 and Bdnf correlate to Fto-expression positively and negatively, respectively, in ad libitum chow fed mice. Pfn2, Stat3 and Btbd12 were positively correlated to expression of Fto in hypothalami of 16 hour food restricted mice.