Alignment of the predicted protein sequences of zebrafish and human Kv3.3. Protein sequences of kcnc3a, kcnc3b, and human Kv3.3 encompassing the amino terminus, S1-S6 membrane domain, and proximal carboxyl terminus were aligned using Clustal W (1.81) . Sequences of the distal carboxyl termini in kcnc3a and kcnc3b are provided in Fig. 4D. Accession numbers: kcnc3a sequence with 'WIKP' ending, [GenBank: HQ118212]; kcnc3a sequence with 'PSIL' ending, [GenBank: HQ118213]; kcnc3b sequence, [GenBank:HQ118214].