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Figure 3 | BMC Neuroscience

Figure 3

From: Automated quantitative gait analysis in animal models of movement disorders

Figure 3

Motor deficits following unilateral lesioning in rat basal ganglia using 6-OHDA. (A) Proportion of limb use of 'lesioned' paws in 6-OHDA experimental groups as well as in normal rats and sham controls as measured in the limb-use asymmetry ('cylinder') test. Dashed line at 50% indicates the average expected paw usage in normal rats. (B) Deficits in pawprint intensity recorded via the catwalk method (expressed as % difference of contralateral vs. ipsilateral forepaws) in 6-OHDA medial forebrain bundle lesion or sham rats at 1 and 2 weeks post-lesion. (C) Deficits in pawprint intensity recorded via the catwalk method (expressed as % difference of contralateral vs. ipsilateral forepaws) in 6-OHDA striatal lesion or sham rats at 3 days, 1, 2 and 3 weeks post-lesion. Data are shown as mean ± s.e.m. * p < 0.05.

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