Figure 15

Tissue distribution data for intramuscular [¹²⁵I]-WGA. Results are standardized by dividing all results for a given animal by the cpm/mg in blood for that animal. This results in a dimensionless figure proportional to concentration in tissue relative to concentration in blood for each tissue in each animal. Data are arrayed in chronological experimental sequence order as follows: (a) and (b) - incision with suture closure and 3 day survival; (c) - similar to (a) & (b) but longer survival time; (d) - superglue seal on the incision, animals kept in a metabolic cage; (e), (f), and (g) - the [¹²⁵I]-WGA was concentrated into one tenth the volume; (h) - large dose with 20 injection locations of 0.5 microliters each and longer survival; (i) and (j) - ten small injections; (k) - 10 gm-cm spinal cord injury; (l)- 25 gm-cm spinal cord injury; (m) - very long survival of 10 days (multiplied by 10 to emphasize very low retention).