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Figure 1 | BMC Neuroscience

Figure 1

From: Tri-partite complex for axonal transport drug delivery achieves pharmacological effect

Figure 1

Tripartite delivery vehicle. (a) The drug delivery vehicles include a targeting element - the axonal transport facilitator or ATF (blue sphere), and a polymer such as dextran (red repeating units) that carry multiple drug molecules (purple). (b) They are designed to be injected in muscle or skin and then travel via an "intraneural" route to deliver the drug molecules to the cell body. (c) Late during transport and on arrival in the cell body, lytic processes release the active drug molecule by breakdown of the linker components.

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