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Figure 5 | BMC Neuroscience

Figure 5

From: Lipopolysaccharide-induced inflammation attenuates taste progenitor cell proliferation and shortens the life span of taste bud cells

Figure 5

The effects of LPS on perigemmal keratinocyte turnover. A, Time course of the number of BrdU-labeled perigemmal cells/mm2 in circumvallate epithelium of PBS- or LPS-treated mice. Solid lines indicate the time course curves. Dashed lines show where the numbers of BrdU-labeled perigemmal cells reached half-maximum values for each group. The numbers above the dashed lines are the average turnover periods for the perigemmal keratinocytes in the circumvallate epithelium (4.2 days for the PBS group and 3.9 days for the LPS group). B, Average number of BrdU-labeled cells/mm2 in the perigemmal region of circumvallate epithelium 1 day after BrdU injection. LPS treatment significantly decreased the number of BrdU-labeled perigemmal cells. Error bars indicate SEM. ** p < 0.005.

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