Table 1 Cox regression analysis in Hk mutants (A, C) and their wild-type siblings (B, D)
A | Â | Â | Â | Â |
|---|---|---|---|---|
Line | Days | Variable | Regression coefficient (×102) | P |
HkY | 14 d | Total Sleep | -4.32 | <0.0001 |
| Â | 28 d | Total Sleep | -5.43 | <0.0001 |
Hk1 | 14 d | Total Sleep | -4.94 | <0.0001 |
| Â | 28 d | Total Sleep | -5.76 | <0.0001 |
Hk2 | 14 d | Total Sleep | 0.855 | 0.259 |
| Â | 28 d | Total Sleep | -1.09 | 0.152 |
B | Â | Â | Â | Â |
Wt-HkY | 14 d | Total Sleep | -2.02 | 0.022 |
| Â | 28 d | Total Sleep | -2.06 | 0.023 |
Wt-Hk1 | 14 d | Total Sleep | -5.42 | <0.0001 |
| Â | 28 d | Total Sleep | -5.38 | <0.0001 |
Wt-Hk2 | 14 d | Total Sleep | -1.16 | 0.178 |
| Â | 28 d | Total Sleep | -1.47 | 0.083 |
C | Â | Â | Â | Â |
HkY | 14 d | Total Activity | 1.63 | <0.0001 |
| Â | 28 d | Total Activity | 1.42 | <0.0001 |
Hk1 | 14 d | Total Activity | 1.63 | <0.0001 |
| Â | 28 d | Total Activity | 1.26 | <0.0001 |
Hk2 | 14 d | Total Activity | 0.454 | 0.289 |
| Â | 28 d | Total Activity | 0.774 | 0.078 |
D | Â | Â | Â | Â |
Wt-HkY | 14 d | Total Activity | 1.04 | 0.012 |
| Â | 28 d | Total Activity | 1.22 | 0.011 |
Wt-Hk1 | 14 d | Total Activity | 1.83 | <0.0001 |
| Â | 28 d | Total Activity | 2.13 | <0.0001 |
Wt-Hk2 | 14 d | Total Activity | 0.032 | 0.948 |
| Â | 28 d | Total Activity | 0.234 | 0.668 |