Figure 5

Iodine deficiency and hypothyroidism up-regulated NCAM-180 in hippocampal subregions. ID, iodine-deficient group. The upper bands (A) are representative findings for pups following developmental iodine deficiency and hypothyroidisms. The lower bar graphs indicate the results of the semi-quantitative measurement of NCAM-180 induced by developmental iodine deficiency and hypothyroidisms, for the CA1 (B), CA3 (C), and DG (D) regions. The height of each bar represents the mean ± SD. At each time point, * indicates a significant difference from the control group, p < 0.05 (n = 3).