Figure 6
From: G-CSF protects motoneurons against axotomy-induced apoptotic death in neonatal mice
Size distribution of surviving neurons in the spinal cord of neonatal mice following sciatic nerve axotomy. On the contralateral side (hatched bars) the size distribution between the three genotypes is similar. On the ipsilateral side (filled bars) there is a downward shift in the mean size of the surviving motoneurons in the littermates without overexpression of G-CSF (BEG -/- CaMK -/-; BEG -/T CaMK -/-). (p < 0.0001 for BEG -/T CaMK -/T vs. BEG -/- CaMK -/-; **p = 0.0008 for BEG -/T CaMK -/T vs. BEG -/T CaMK -/-; ANOVA followed by Fisher's LSD; Number of motoneurons measured: wt, n = 301; BEG -/T CaMK -/-, n = 197; BEG -/T CaMK -/T, n = 227).