Table 1 Brain donor information
From: Apolipoprotein-E forms dimers in human frontal cortex and hippocampus
Case # | Diagnosis | Sex | APOE genotype | Age at death | PMI | Brain regions analysed | ApoE homodimer as % of total apoE |
|---|---|---|---|---|---|---|---|
CON 1 | Normal | F | ϵ3/ϵ3 | 73 | 60 | FC; H | 23.5; 11.4 |
CON 2 | Normal | F | ϵ3/ϵ3 | 83 | 24 | FC; H | 21.3; 9.1 |
CON 3 | Normal | F | ϵ3/ϵ3 | 77 | 36 | FC | 4.2 |
CON 4 | Normal | M | ϵ3/ϵ3 | 79 | 60 | FC; H | 16.7; 10 |
CON 5 | Normal | M | ϵ3/ϵ3 | 82 | 43 | FC; H | 33.4; 6.6 |
CON 6 | Normal | F | ϵ3/ϵ3 | 93 | 21 | FC; H | 2.47; 6.15 |
CON 7 | Normal | F | ϵ3/ϵ3 | 85 | 23 | FC; H | 13.73; 6.75 |
AD 1 | AD | F | ϵ3/ϵ3 | 79 | 4 | FC | 4.4 |
AD 2 | AD | M | ϵ3/ϵ3 | 60 | 2 | FC | 10.4 |
AD 3 | AD | M | ϵ3/ϵ3 | 75 | 1 | FC | 19.13 |
AD 4 | AD | M | ϵ3/ϵ3 | 70 | 35 | FC; H | 12.55; 7.56 |
AD 5 | AD | F | ϵ3/ϵ3 | 94 | 7 | FC; H | 9.54; 12.16 |
AD 6 | AD | F | ϵ3/ϵ4 | 83 | 3 | FC | 3.61 |
AD 7 | AD | M | ϵ3/ϵ4 | 73 | 16 | FC | 2.28 |
AD 8 | FAD | F | ϵ3/ϵ4 | 47 | 69 | FC | 4.94 |
AD 9 | FAD | M | ϵ3/ϵ4 | 51 | 5 | FC | 5.2 |
AD 10 | AD | M | ϵ3/ϵ4 | 83 | 36 | FC | 5.88 |
AD 11 | AD | M | ϵ4/ϵ4 | 74 | 5 | FC; H | 0 |
AD 12 | AD | F | ϵ4/ϵ4 | 75 | 80 | FC | 0 |
AD 13 | AD | F | ϵ4/ϵ4 | 68 | 44 | FC | 0 |
AD 14 | AD | M | ϵ4/ϵ4 | 83 | 25 | FC | 0 |
AD 15 | AD | F | ϵ4/ϵ4 | 78 | 24 | FC | 0 |
AD 16 | AD | M | ϵ4/ϵ4 | 67 | 60 | FC | 0 |
AD 17 | AD | F | ϵ4/ϵ4 | 84 | 74 | FC | 0 |