Figure 4
Influence of ATX on sodium influx in HEK 293 and rNa v 1.4-HEK 293, or CHL 1610 and rNa v 1.5-CHL 1610 cells. Time-response relationships for ATX induced sodium influx in rNav1.4-HEK 293 (a), HEK 293 (b) rNav1.5-CHL1610 (d) and CHL1610 cells (e); Concentration-response relationships for ATX-induced sodium influx in rNav1.4-HEK 293 and HEK 293 (c), and CHL 1610 and rNav1.5-CHL 1610 cells (f). These data were obtained from at least two different cultures performed in triplicate.