Figure 2
From: Viable mouse gene ablations that robustly alter brain Aβ levels are rare
Primary screen of Aβ40 levels. Panel A - The median values of Aβ40 relative to baseline for each of 1930 KO strains is shown in red. Assay plate values for BACE1, BACE2 double KO brains are shown in blue, and values for Aβ1-14 synthetic peptide-blocked wild type brains are shown in green. The results for the PIGZ KO and the QPRT KO are indicated by arrows. Panel B - Same as panel A, except mean values of Aβ40 are plotted.