Changes in uMtCK (A, B), BCK (C, D) and CRT (E, F) immunoreactivity in the rat hippocampus at 2 hr after PILO injection: (A, C, E) saline-treated animal; (B, D, F) PILO-treated animal. uMtCK immunoreactivity is unaffected by PILO-induce seizure activity. However, both BCK and CRT immunoreactivities are markedly reduced in the rat hippocampus at 2 hr after PILO injection. Rectangles in panels 1 indicate the regions of panels 2 and 3. Bar = 200 (panel 1) and 25 (panels 2-4) μm.