Figure 2

Determination of proDYN mRNA expression levels in the spinal cord after reinflammation using real-time RT-PCR. A significant increase in proDYN mRNA expression was found in the neonatal CFA group compared with the neonatal non-treated and neonatal saline groups 24 h after reinflammation with CFA (* P < 0.05). No significant differences in proDYN expression levels was noted between the neonatal non-treated group and the neonatal saline group. Little or no proDYN expression was noted in the naïve group, which did not receive any CFA injection during the neonatal and the adult time.