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Figure 3 | BMC Neuroscience

Figure 3

From: Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca2+ permeability and Mg2+block

Figure 3

Mg2+ block of coexpressed mutant NMDAR subunits: IV relations. IV relationships of the Mg2+ block of N and N+1 site mutant NMDAR diheteromers. Shown are measurements between -150 mV and +50 mV after application of 10 μM glycine (Gly) alone or in coapplication with 100 μM glutamate (Glu) in the absence (blue traces) and presence (red bars) of Mg2+. Traces represent averages from 3-4 experiments per subunit combination (normalized to +20 mV).

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