Gene expression profiling in brain of mice exposed to the marine neurotoxin ciguatoxin reveals an acute anti-inflammatory, neuroprotective response

Table 3 Significantly altered genes common to brain, liver and blood.

Accession #	Sequence Description	1 hr	4 hr
NM_019440	Immunity-related GTPase family M member 2 (Irgm2)		↑
NM_029000	GTPase, very large interferon inducible 1 (Gvin1)		↓
AF053745	Glycosylated gag protein (Mus dunni endogenous virus)		↑
NM_007705	Cold inducible RNA binding protein (Cirbp)		↑
NM_008245	Hematopoietically expressed homeobox (Hhex)	↓
NM_026268	Dual specificity phosphatase 6 (Dusp6)		↓
NM_008361	Interleukin 1 beta (Il1b)		↓
NM_010220	FK506 binding protein 5 (Fkbp5)	↑	↑
BC057864	Polymeric immunoglobulin receptor 3 precursor (Pigr3)	↑	↑
NM_008330	Interferon gamma inducible protein		↓
NM_007679	CCAAT/enhancer binding protein (C/EBP), delta
NM_010907	NFkB inhibitor, alpha (Nfkbia)	↑	↑
NM_016693	Mitogen-activated protein kinase kinase kinase 6 (Map3k6)		↑
BC021340	Poly (ADP-ribose) polymerase family, member 14 (Parp 14)		↓
NM_007482	Arginase 1 (Arg1)

Arrows indicate where gene expression was in the same direction for all three tissues, when at least 2 tissues reported statistically significant data. Blank cells were largely due to the lack of significant data from more than 1 tissue at that particular time point.

ISSN: 1471-2202