Table 1 Comparison of Gene Ontology and metabolic pathway enrichment by cluster metric (Euclidean vs Pearson) for medium stringency dataset.
Pearson metric - Cluster 1 d - Biological Process | Genes | % input | P-Value | Benjam |
|---|---|---|---|---|
response to wounding | 28 | 10.6 | 1.7E-15 | 9.2E-12 |
acute inflammatory response | 17 | 6.4 | 2.6E-15 | 6.9E-12 |
response to external stimulus | 32 | 12.1 | 5.6E-14 | 9.6E-11 |
inflammatory response | 20 | 7.6 | 4.3E-11 | 5.6E-08 |
acute-phase response | 9 | 3.4 | 7.8E-10 | 8.1E-07 |
response to stress | 31 | 11.7 | 1.0E-07 | 9.0E-05 |
electron transport | 22 | 8.3 | 2.4E-07 | 1.7E-04 |
complement activation | 8 | 3 | 9.5E-07 | 6.2E-04 |
activ of plasma proteins in acute inflam response | 8 | 3 | 9.5E-07 | 6.2E-04 |
complement activation, classical pathway | 7 | 2.7 | 1.2E-06 | 6.0E-04 |
wound healing | 10 | 3.8 | 1.8E-06 | 8.5E-04 |
generation of precursor metabolites and energy | 23 | 8.7 | 2.3E-06 | 1.0E-03 |
humoral immune response by immunoglobulin | 7 | 2.7 | 3.7E-06 | 1.5E-03 |
complement activation, alternative pathway | 5 | 1.9 | 4.3E-06 | 1.6E-03 |
blood coagulation | 8 | 3 | 8.1E-06 | 2.8E-03 |
coagulation | 8 | 3 | 9.1E-06 | 2.9E-03 |
defense response | 25 | 9.5 | 9.1E-06 | 2.8E-03 |
hemostasis | 8 | 3 | 1.1E-05 | 3.2E-03 |
regulation of body fluid levels | 8 | 3 | 5.0E-05 | 1.4E-02 |
activation of immune response | 8 | 3 | 7.4E-05 | 1.9E-02 |
regulation of multicellular organismal process | 14 | 5.3 | 1.1E-04 | 2.7E-02 |
regulation of immune response | 9 | 3.4 | 1.4E-04 | 3.3E-02 |
immune response | 19 | 7.2 | 1.5E-04 | 3.4E-02 |
regulation of immune system process | 9 | 3.4 | 1.6E-04 | 3.3E-02 |
positive reg of multicellular organismal process | 9 | 3.4 | 2.2E-04 | 4.4E-02 |
innate immune response | 8 | 3 | 2.2E-04 | 4.4E-02 |
Euclidian metric - Cluster 1g - Biological Process | Genes | % input | P-Value | Benjam |
acute inflammatory response | 8 | 3.8 | 1.5E-05 | 7.5E-02 |
humoral immune response by immunoglobulin | 6 | 2.8 | 2.1E-05 | 5.3E-02 |
response to external stimulus | 17 | 8.1 | 2.7E-05 | 4.6E-02 |
Euclidian metric - Cluster 1f - Biological Process | Â | Â | Â | Â |
response to wounding | 16 | 24.6 | 3.4E-14 | 1.7E-10 |
response to external stimulus | 17 | 26.2 | 1.4E-12 | 3.6E-09 |
acute inflammatory response | 9 | 13.8 | 1.8E-10 | 3.1E-07 |
acute-phase response | 7 | 10.8 | 2.2E-10 | 2.9E-07 |
response to stress | 17 | 26.2 | 3.4E-09 | 3.5E-06 |
wound healing | 8 | 12.3 | 1.6E-08 | 1.4E-05 |
inflammatory response | 10 | 15.4 | 3.6E-08 | 2.7E-05 |
blood coagulation | 6 | 9.2 | 1.3E-06 | 8.5E-04 |
coagulation | 6 | 9.2 | 1.4E-06 | 8.2E-04 |
hemostasis | 6 | 9.2 | 1.7E-06 | 8.7E-04 |
regulation of body fluid levels | 6 | 9.2 | 5.2E-06 | 2.4E-03 |
defense response | 11 | 16.9 | 8.4E-05 | 3.6E-02 |