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Table 2 CA molecules released from control and shRNA-syt I knockdown cells transfected with pSyt IV.

From: Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown

  Average Number of CA Molecules/cell (× 106) ± SEM (× 106) Number of Cells
Control 56.7 ± 7.2 16
pSyt IV-Control 64.3 ± 13.8 13
shRNA-syt Ia 16.0 ± 2.9** 16
pSyt IV-shRNA-syt Ia 11.1 ± 2.3+ 17
shRNA-syt Ib 33.2 ± 7.8* 20
pSyt IV-shRNA-syt Ib 11.0 ± 2.4+,± 17
  1. The Faraday equation was used to calculate the average number of CA molecules per cell from the total charge per cell [44] (*p < 0.05 and **p < 0.01 compared to control cells; +p < 0.01 compared to pSyt IV control cells; and ±p < 0.05 compared to shRNA-syt Ib cells).
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