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Figure 5 | BMC Neuroscience

Figure 5

From: Hippocampal CA1/subiculum-prefrontal cortical pathways induce plastic changes of nociceptive responses in cingulate and prelimbic areas

Figure 5

Fos staining in prelimbic areas of the PFC. A: An untreated control showed Fos positive cells in the prelimbic area. B: LFS significantly decreased Fos expression in the ipsilateral prelimbic area. C: An untreated control showed Fos positive cells in the cingulate area. Scale lines represent 50 μm. D: Numbers of Fos-expressing cells in the ipsilateral and contralateral prelimbic areas before and after LFS. Fos positive cells were decreased in the prelimbic area. CN: control, LFS: low frequency stimulation *** P < 0.001. E: Numbers of Fos-expressing cells in the ipsilateral and contralateral cingulate areas before and after HFS.

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