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Figure 2 | BMC Neuroscience

Figure 2

From: Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson's disease

Figure 2

(A) Representative T2W MR images from saline-injected control subject with sample ROIs utilised for quantitative volumetric analysis of individual brain regions. (B-G) Bar graphs of regional brain volumetric data measured on in vivo T2W anatomical MRI scans acquired from saline and lactacystin-injected animals 3 weeks post-lesion. (B) Whole brain volume, (C) corpus striatum, (D) ventral midbrain, (E) lateral ventricles, (F) cerebellum and (G) hippocampal formation. Data are expressed as mean volume mm3 ± s.e.m. *p < 0.05, **p < 0.01; ipsilateral vs. contralateral hemisphere; *p < 0.01; ipsilateral hemisphere of lactacystin vs. saline-injected; §p < 0.05 contralateral hemisphere of saline vs. lactacystin-injected.

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