Figure 1
From: Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice
Clinical assessment of mice following EAE induction by MOG peptide. A. Photographs of EAE-induced wildtype (+/+) and AQP4 null (-/-) mice at 19 days after initial MOG immunization. Arrowhead, tail paralysis; arrows, hindlimb weakness/paralysis. See Supplemental Materials for movie. B. EAE clinical score (see Methods) for EAE-induced and control wildtype and AQP4 null mice. C. Mouse body weight. Differences in body weight gain not significant.