In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain

Table 2 Spearman Rank correlation analyses of metabolite concentrations between different brain regions of the SIV infected macaques.

	NAA		Glx		Cr		Cho		MI
Spearman Rank	R _s	p	R _s	P	R _s	p	R _s	p	R _s	p
FC – WM		NS	*0.32*	*0.088*		NS	0.52	0.0032		NS
FC – BG		NS	0.52	0.0034		NS	*0.36*	*0.052*	0.37	0.043
WM – BG	0.50	0.0049		NS		NS	0.54	0.0021		NS

For this purpose the percent change from baseline were calculated for each individual monkey for all time points. Significant P-values are noted in bold. P-values with a trend towards significance (P < 0.1) are noted italics and non-significant differences are indicated by NS. However, it must be noted that when the correlations are subjected to Bonferroni correction, a P-value of < 0.0033 is required for significance.

ISSN: 1471-2202