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Table 3 Levels of MMP-9 and TIMP-1 protein in brain tissue after MCAO and after treatment with U0126 at 0, 6, and 12 hours post occlusion

From: Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat

Brain tissue
  Control MCAO MCAO + U0126 - 0 h MCAO + U0126 - 6 h MCAO + U0126 - 12 h
MMP-9 (%) ± SEM 100 ± 5.8 125 ± 8.0 101 ± 6.5 102 ± 4.7 109 ± 7.2
TIMP-1 (%) ± SEM 100 ± 3.8 113 ± 2.7 111 ± 5 105 ± 2.7 112 ± 5.2
  1. Values are percentages of the control value and are reported as mean ± standard error of the mean (SEM); n = 5–6, *P < 0.05, **P < 0.01, §P < 0.05, §§ P < 0.01. *Indicates a significant difference between the control group and the MCAO group; § indicates a significant difference between the MCAO group and the U0126-treated group.