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Table 2 Levels of MMP-9 and TIMP-1 protein in the microvessels after MCAO and after treatment with U0126 at 0, 6, and 12 hours post occlusion

From: Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat

Cerebral microvessels
  Control MCAO MCAO + U0126 - 0 h MCAO + U0126 - 6 h MCAO + U0126 - 12 h
MMP-9 (%) ± SEM 100 ± 3.5 127 ± 1.5* 90 ± 9.8§ 92.5 ± 4.05§ 97 ± 4.4
TIMP-1 (%) ± SEM 100 ± 5 141 ± 2.6* 104 ± 5.3§ 101 ± 6§ 129 ± 7.3