Table 2 Levels of MMP-9 and TIMP-1 protein in the microvessels after MCAO and after treatment with U0126 at 0, 6, and 12 hours post occlusion
Cerebral microvessels | |||||
|---|---|---|---|---|---|
Control | MCAO | MCAO + U0126 - 0 h | MCAO + U0126 - 6 h | MCAO + U0126 - 12 h | |
MMP-9 (%) ± SEM | 100 ± 3.5 | 127 ± 1.5* | 90 ± 9.8§ | 92.5 ± 4.05§ | 97 ± 4.4 |
TIMP-1 (%) ± SEM | 100 ± 5 | 141 ± 2.6* | 104 ± 5.3§ | 101 ± 6§ | 129 ± 7.3 |