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Table 1 Results of comparisons of gene expression levels for those genes showing differences between brain regions

From: Genes within the serotonergic system are differentially expressed in human brain

Gene

Brain region 1

Brain region 2

Mean Difference

(1–2)

Std. Error

Bonferroni-corrected

p value

95% Confidence Intervals

5-HT2C

CEREBELLUM

SFG

-0.779

0.176

0.001

-1.334

-0.223

  

STG

-1.041

0.179

<0.001

-1.606

-0.476

  

STRIATUM

-1.748

0.173

<0.001

-2.295

-1.201

  

MIDBRAIN

-1.180

0.210

<0.001

-1.843

-0.518

  

THALAMUS

-1.835

0.358

<0.001

-2.965

-0.705

  

HIPPOCAMPUS

-1.338

0.247

<0.001

-2.117

-0.559

 

STRIATUM

SFG

0.969

0.170

<0.001

0.432

1.506

  

STG

0.706

0.173

0.003

0.159

1.253

5-HT2A

CEREBELLUM

SFG

-1.430

0.164

<0.001

-1.948

-0.911

  

STG

-1.427

0.164

<0.001

-1.946

-0.909

  

MIDBRAIN

-0.706

0.196

0.012

-1.324

-0.088

  

STRIATUM

-0.934

0.170

<0.001

-1.471

-0.397

  

HIPPOCAMPUS

-1.267

0.230

<0.001

-1.994

-0.541

 

SFG

MIDBRAIN

0.724

0.193

0.008

0.113

1.335

  

THALAMUS

0.905

0.279

0.039

0.023

1.788

 

STG

MIDBRAIN

0.721

0.193

0.008

0.111

1.332

  

THALAMUS

0.903

0.279

0.040

0.021

1.785

TPH2

CEREBELLUM

SFG

-0.746

0.203

0.011

-1.392

-0.101

  

HIPPOCAMPUS

-1.205

0.277

0.001

-2.087

-0.323

  1. Mean differences were calculated where relative expression values of brain region 2 were subtracted from the value of brain region 1. The significance levels and 95% confidence levels are listed for comparisons that show significant differences only.