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Table 1 Summary of in vivo RGC counts. Systemic and topical application of G-CSF or vehicle.

From: Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy

Experimental Group Animal RGCs per mm2 Mean S.E.M.
axotomy + vehicle injection s.c. 1 360   
  2 348   
  3 594   
  4 379 420.6 58.4
axotomy + vehicle injection i.o. 1 443   
  2 390   
  3 378   
  4 435   
  5 365 402.2 15.5
axotomy + G-CSF 20 μg/kg BW s.c. daily 1 669   
  2 442   
  3 554   
  4 649 578.9 52.0
axotomy + G-CSF 40 μg/kg BW s.c. daily 1 729   
  2 637   
  3 778   
  4 704   
  5 773 742.3 25.8
axotomy + G-CSF 40 μg/kg BW s.c. daily (start 1 d before surgery) 1 641   
  2 876   
  3 696   
  4 872 771.3 60.3
axotomy + G-CSF 500 ng i.o. on days 0, 4, 7 and 10 after axotomy 1 638   
  2 613   
  3 773   
  4 703 681.8 35.8
  1. Cell numbers are given as mean ± S.E.M. s.c.: subcutaneous; i.o.: intraocular; BW: bodyweight.