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Table 2 Brain areas with regional white matter volume changes and MTR reductions (TS versus controls)

From: Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imaging

Cluster size Regions (Brodmann areas) MNI-Space t-value p-value
(SVC)
   x y z   
WMV: controls > TS
157 Right inferior frontal gyrus (9) 44 3 25 4.35 0.010
81 Left superior frontal gyrus (6) -16 15 54 4.05 0.021
33 Left precentral gyrus (6) -25 -20 70 3.93 0.027
115 Right anterior corpus callosum 7 34 10 3.92 0.028
79 Left lingual gyrus (18) -32 -77 -12 3.82 -
WMV: TS > controls
267 Left postcentral gyrus (43) -54 -10 20 5.02 0.005
344 Left precentral gyrus (6) -26 -12 53 4.00 0.023
  Left middle frontal gyrus (6) -19 -11 62 3.74 0.031
42 Left precentral gyrus (4) -45 -18 38 3.60 0.056
34 Right parahippocampal gyrus (30) 27 -46 6 3.49 0.060
10 Right precentral gyrus (44) 49 10 11 3.39 0.085
MTR maps: controls > TS
99 Right medial frontal gyrus (9) 17 32 37 3,75 0.036
33 Right inferior frontal gyrus (46) 40 32 12 3,65 0.045
33 Left inferior frontal gyrus (46) -41 24 13 3,63 0.041
17 Right cingulate gyrus (32) 11 22 43 3,45 0.048
  1. MNI = Montreal Neurological Institute, SVC = small volume correction, WMV = white matter volume, MTR = magnetization transfer ratio, TS = Tourette syndrome. No regions displayed significant regional increases in MTR maps for TS patients versus controls.