Skip to main content

Table 1 Estimates of proliferating cells, young neurons and pyknotic cells in the dentate gyrus

From: No effect of running and laboratory housing on adult hippocampal neurogenesis in wild caught long-tailed wood mouse

  baseline control running CE Sampling sites* Sections analyzed* Cells counted*
Ki67 4'047 4'315 4'744 0.049   14 (12–15) 695 (356–1001)
SD 772 1'525 977     
DCX 15'840 15'204 14'871 0.09 339(273–486) 14 (10–16) 157 (64–319)
SD 5'426 7'238 4'019     
pyknotic 223 279 283 0.09   27 (21–30) 48 (17–78)
SD 148 122 110     
  1. Average numbers of young neurons, visualized immunohistochemically through Doublecortin (DCX), are obtained from stereological estimates using the optical fractionator method. Proliferating cells (Ki67 positive cells) and pyknotic cells are counted manually and multiplied by the section fraction to estimate total cell numbers. All parameters were analyzed in every sixth section. SD stands for standard deviation and CE is coefficient of error. *Values are means with ranges in parentheses.