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Figure 1 | BMC Neuroscience

Figure 1

From: Effects of NR1 splicing on NR1/NR3B-type excitatory glycine receptors

Figure 1

Comparison of agonist-induced currents for all NR1 splice variant/NR3B combinations. A. Ratio of current responses elicited by application of glycine (10 μM, Gly) and glycine plus glutamate (300 μM, Glu) for NR1 subunits expressed alone, NR1/NR2B heteromers, and NR1/NR3B heteromers. Data shown here are mean values ± SEM, n = 10–23 from 2–5 independent experiments per combination; *p < 0.05; **p < 0.01; ***p < 0.005 (Student's t-test). B. Representative current traces of diheteromers, shown exemplary for combinations with NR1–3a. Black bars denote agonist application.

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