Figure 4From: A mathematical model of aging-related and cortisol induced hippocampal dysfunctionResponse of the model to negative feedback of cortisol regulation from a) the hypothalamus and b) pituitary c) increased CRH and d) decreased CRH production. Parameters were changed by a factor of 10–50% inducing changes in circulating cortisol levels as described in accompanying tables, modelled using SBML as detailed in the methods section.Back to article page