TY - JOUR AU - Buhler, Lillian A. AU - Samara, Ramsey AU - Guzman, Esther AU - Wilson, Carole L. AU - Krizanac-Bengez, Liljana AU - Janigro, Damir AU - Ethell, Douglas W. PY - 2009 DA - 2009/03/06 TI - Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis JO - BMC Neuroscience SP - 17 VL - 10 IS - 1 AB - Metalloproteinase inhibitors can protect mice against experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS). Matrix metalloproteinase-9 (MMP-9) has been implicated, but it is not clear if other MMPs are also involved, including matrilysin/MMP-7 – an enzyme capable of cleaving proteins that are essential for blood brain barrier integrity and immune suppression. SN - 1471-2202 UR - https://doi.org/10.1186/1471-2202-10-17 DO - 10.1186/1471-2202-10-17 ID - Buhler2009 ER -