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Table 1 ID and PTU-induced hypothyroidism reduced pups body weight (g)

From: Developmental iodine deficiency resulting in hypothyroidism reduces hippocampal ERK1/2 and CREB in lactational and adolescent rats

Time

N

Control

5 ppm-PTU

15 ppm-PTU

ID

PN3

259

8.37 ± 0.12

7.06 ± 0.09 *

6.73 ± 0.11 *#

5.86 ± 0.08 *#Δ

PN7

252

13.79 ± 0.22

11.02 ± 0.17 *

10.66 ± 0.19 *

7.39 ± 0.15 *#Δ

PN10

231

20.13 ± 0.40

15.12 ± 0.16 *

14.29 ± 0.33 *

8.58 ± 0.22 *#Δ

PN14

217

26.43 ± 0.48

19.53 ± 0.24 *

18.09 ± 0.39 *#

10.43 ± 0.26 *#Δ

PN18

171

35.55 ± 0.59

25.96 ± 0.48 *

22.57 ± 0.53 *#

12.93 ± 0.46 *#Δ

PN21

140

44.83 ± 0.80

28.64 ± 0.73 *

25.05 ± 0.68 *#

14.41 ± 0.61 *#Δ

PN25

101

56.80 ± 1.39

38.97 ± 2.04 *

32.33 ± 1.27 *#

17.95 ± 1.04 *#Δ

PN28

101

74.22 ± 1.74

49.56 ± 1.97 *

37.14 ± 2.07 *#

21.41 ± 1.28 *#Δ

PN31

71

100.58 ± 2.52

69.31 ± 3.28 *

53.69 ± 4.27 *#

26.56 ± 1.69 *#Δ

PN35

71

126.30 ± 2.88

90.26 ± 3.85 *

72.17 ± 5.75 *#

40.94 ± 2.03 *#Δ

PN42

45

155.86 ± 6.11

127.09 ± 3.99 *

112.33 ± 7.40 *

69.41 ± 3.33 *#Δ

  1. The pup weights of iodine-deficient, 15 ppm and 5 ppm PTU-treatment groups were significantly lower than controls from PN3 to PN42. Each values represents mean ± SEM. *P < 0.05, as compared to control group. #P < 0.05, as compared to 5 ppm PTU-treatment group. ΔP < 0.05, as compared to 15 ppm PTU-treatment group.