Skip to main content

Table 1 ID and PTU-induced hypothyroidism reduced pups body weight (g)

From: Developmental iodine deficiency resulting in hypothyroidism reduces hippocampal ERK1/2 and CREB in lactational and adolescent rats

Time N Control 5 ppm-PTU 15 ppm-PTU ID
PN3 259 8.37 ± 0.12 7.06 ± 0.09 * 6.73 ± 0.11 *# 5.86 ± 0.08 *
PN7 252 13.79 ± 0.22 11.02 ± 0.17 * 10.66 ± 0.19 * 7.39 ± 0.15 *
PN10 231 20.13 ± 0.40 15.12 ± 0.16 * 14.29 ± 0.33 * 8.58 ± 0.22 *
PN14 217 26.43 ± 0.48 19.53 ± 0.24 * 18.09 ± 0.39 *# 10.43 ± 0.26 *
PN18 171 35.55 ± 0.59 25.96 ± 0.48 * 22.57 ± 0.53 *# 12.93 ± 0.46 *
PN21 140 44.83 ± 0.80 28.64 ± 0.73 * 25.05 ± 0.68 *# 14.41 ± 0.61 *
PN25 101 56.80 ± 1.39 38.97 ± 2.04 * 32.33 ± 1.27 *# 17.95 ± 1.04 *
PN28 101 74.22 ± 1.74 49.56 ± 1.97 * 37.14 ± 2.07 *# 21.41 ± 1.28 *
PN31 71 100.58 ± 2.52 69.31 ± 3.28 * 53.69 ± 4.27 *# 26.56 ± 1.69 *
PN35 71 126.30 ± 2.88 90.26 ± 3.85 * 72.17 ± 5.75 *# 40.94 ± 2.03 *
PN42 45 155.86 ± 6.11 127.09 ± 3.99 * 112.33 ± 7.40 * 69.41 ± 3.33 *
  1. The pup weights of iodine-deficient, 15 ppm and 5 ppm PTU-treatment groups were significantly lower than controls from PN3 to PN42. Each values represents mean ± SEM. *P < 0.05, as compared to control group. #P < 0.05, as compared to 5 ppm PTU-treatment group. ΔP < 0.05, as compared to 15 ppm PTU-treatment group.