Figure 3

MDN resting state connectivity analysis. A: Probabilistic maps of the MDN rsFC Amygdale projection relative to healthy subjects. B: Probabilistic maps of the MDN rsFC Amygdale projection relative to pain subjects. C: Group comparison of the MDN rsFC Amygdale projection. D: Group comparison of the MDN rsFC Subgenual ACC projection. E: Group comparison of the MDN rsFC S1 projection. Colors from green to white indicate an increasing spatial overlapping probability (%) (single subject correlation maps before probability map creation thresholded at q<0.05 FDR-corrected, minimum cluster dimension K>5 voxels in the native resolution). Group comparison with two sample t-test, q<0.05 FDR-corrected, minimum cluster dimension K>5 voxels in the native resolution; colors from red to yellow indicate an increased connectivity in the pain group; colors from blue to green indicate a reduced connectivity in the pain group. All rsFC maps were projected on 3D representation of the brain using BrainVoyager QX.