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Table 1 Comparison of focal-cortical and systemic models at 3 h

From: Status epilepticus affects the gigantocellular network of the pontine reticular formation

4-AP crystal (n = 4)

4-AP i.p. (n = 4)

Pilocarpine (n = 6)

Kainic Acid (n = 8)

i.d.

PRF

DN

Bhv.

scr.

SE

EEG

i.d.

PRF

DN

Bhv.

scr.

SE

EEG

i.d.

PRF

DN

Bhv.

scr.

SE

EEG

i.d.

PRF

DN

Bhv.

scr.

SE

EEG

ac1

-

3

-

 

ai1

-

3

-

 

pi1

-

3

-

 

ka1E

+++

4

+

5

ac2

++

5

+

 

ai2

-

3

-

 

pi2

+

5

+

 

ka2E

+

3

-

3

ac3

+++

5

+

 

ai3

++

5

+

 

pi3

+++

5

+

 

ka3E

+++

4

+

5

ac4E

+++

5

+

5

ai4

+++

5

+

 

pi4E

+++

5

+

5

ka4E

-

3

-

2

          

pi5

+++

5

+

      
          

pi6E

+++

5

+

5

     
     

ak1

 

2

-

 

pk1

 

2

-

 

ak1

++

5

+

 
     

ak2E

 

3

-

1

pk2

 

2

-

 

ak2E

+++

5

+

5

               

pk1

+

4

-

 
               

pk2

++

5

+

 
  1. i.d.: animal i.d., PRF DN: number of „dark” neurons in the PRF, Bhv.scr.: behavioral scoring with Racine Scale; SE: if Status Epilepticus developed (+) or not (-), EEG: Treiman's EEG phases,
  2. The relative numbers of "dark" neurons averaged from five 60-μm sections of the pontine and medullar reticular formation are expressed with a semi-quantitative grading scale as follows: +: 1-5 "dark" neurons; ++: 5-15 "dark" neurons, +++: 15-30 "dark" neurons.