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Figure 7 | BMC Neuroscience

Figure 7

From: A novel role of dendritic gap junction and mechanisms underlying its interaction with thalamocortical conductance in fast spiking inhibitory neurons

Figure 7

Mechanisms underlying TC and EPJP interaction: temporal summation of EPJP and TC. A1) Current-clamp recording of AP (black trace) and voltage-clamp recording of EPJC (gray trace) in a FS pair from brain slice. A2) Voltage-clamp recording of TC -EPSCs in a FS cell. B1&B2) A subthreshold (B1) and suprathreshold (B2) TC induced response in a presynaptic FS cell (black, current clamp) and its postsynaptic responses in another FS cell (gray, voltage-clamp), respectively. C1) Normalized conductance curve of EPJP (induced by single AP) and TC-EPSC in real FS neurons (averaged from 6 cells). C2) Temporal properties of TC-EPSC and EPJP summations measured in FS pairs. Solid line: linear fitting (R = 0.81, p < 0.001).

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BMC Neuroscience

ISSN: 1471-2202

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