Skip to main content
Figure 3 | BMC Neuroscience

Figure 3

From: A novel role of dendritic gap junction and mechanisms underlying its interaction with thalamocortical conductance in fast spiking inhibitory neurons

Figure 3

Simulation and electrophysiological recordings of GJ-mediated responses in model and real FS pairs. A1-3) Current injections (100 pA, 30 ms) in the model FS cell (black traces) induced postsynaptic responses (gray traces) in the postsynaptic model cell connected via GJs of varying strength (0, 0.1 and 0.3 nS). B1) AP (gray trace) in cell 2 induced IPSPs (black) in cell 1 with 50 μM carbenoxalone. B2 & B3) With carbenoxalone, current injection in cell 1 (black) or cell 2 (gray) induced initial depolarizing responses mediated by EPJPs followed by IPSPs.

Back to article page

BMC Neuroscience

ISSN: 1471-2202

Contact us